Počet záznamů: 1

DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: Thermodynamic analysis and chemical probing

  1. 1.
    0366089 - BFU-R 2012 RIV DE eng J - Článek v odborném periodiku
    Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
    DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: Thermodynamic analysis and chemical probing.
    Chemistry-An Asian Journal. Roč. 6, č. 6 (2011), s. 1566-1574 ISSN 1861-4728
    Grant CEP: GA MŠk(CZ) LC06030; GA MŠk(CZ) ME10066; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598; GA ČR(CZ) GAP205/11/0856
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: calorimetry * DNA damage * interstrand cross-link
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 4.500, rok: 2011

    The results show that 1,4-interstrand cross-links formed by BBR3464 between two guanine bases in apposite strands exist as two distinct conformers, which are not interconvertible, not only if these cross-links are formed in the 5'-5', but also in the unusual 3'-3' direction.
    Trvalý link: http://hdl.handle.net/11104/0201180