Počet záznamů: 1

Cytokinin Modulates Endocytic Trafficking of PIN1 Auxin Efflux Carrier to Control Plant Organogenesis

  1. 1.
    0366038 - UEB-Q 2012 RIV US eng J - Článek v odborném periodiku
    Marhavý, P. - Bielach, A. - Abas, L. - Abuzeineh, A. - Duclercq, J. - Tanaka, H. - Pařezová, Markéta - Petrášek, Jan - Friml, J. - Kleine-Vehn, J. - Benková, E.
    Cytokinin Modulates Endocytic Trafficking of PIN1 Auxin Efflux Carrier to Control Plant Organogenesis.
    Developmental Cell. Roč. 21, č. 4 (2011), s. 796-804 ISSN 1534-5807
    Grant CEP: GA AV ČR(CZ) IAA601630703; GA MŠk(CZ) LC06034
    Výzkumný záměr: CEZ:AV0Z50380511
    Klíčová slova: auxin efflux * cytokinin * vacuoles * membrane trafficking
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 14.030, rok: 2011

    Cytokinin is an important regulator of plant growth and development. In Arabidopsis thaliana, the two component phosphorelay mediated through a family of histidine kinases and response regulators is recognized as the principal cytokinin signal transduction mechanism activating the complex transcriptional response to control various developmental processes. Here, we identified an alternative mode of cytokinin action that uses endocytic trafficking as a means to direct plant organogenesis. This activity occurs downstream of known cytokinin receptors but through a branch of the cytokinin signaling pathway that does not involve transcriptional regulation. We show that cytokinin regulates endocytic recycling of the auxin efflux carrier PINFORMED1 (PIN1) by redirecting it for lytic degradation in vacuoles. Stimulation of the lytic PIN1 degradation is specific mechanism to rapidly modulate the auxin distribution in cytokinin-mediated developmental processes.
    Trvalý link: http://hdl.handle.net/11104/0201138