Počet záznamů: 1

Antibacterial nanofiber materials activated by light

  1. 1.
    0365985 - UFCH-W 2012 RIV US eng J - Článek v odborném periodiku
    Jesenská, S. - Plištil, L. - Kubát, Pavel - Lang, Kamil - Brožová, Libuše - Popelka, Štěpán - Szatmáry, Lórant - Mosinger, Jiří
    Antibacterial nanofiber materials activated by light.
    Journal of Biomedical Materials Research. Part A. 99A, č. 4 (2011), s. 676-683 ISSN 1549-3296
    Grant CEP: GA ČR GAP208/10/1678
    Výzkumný záměr: CEZ:AV0Z40400503; CEZ:AV0Z40320502; CEZ:AV0Z40500505
    Klíčová slova: antibacterial nanofiber materials * photoactive * singlet oxygen
    Kód oboru RIV: CF - Fyzikální chemie a teoretická chemie
    Impakt faktor: 2.625, rok: 2011

    Electrospun polymeric nanofiber materials doped with 5,10,15,20-tetraphenylporphyrin (TPP) photosensitizer were prepared from four different polymers and were characterized with microscopic methods, steady-state, and time-resolved fluorescence and absorption spectroscopy. The polymers used included polyurethane Larithane™ (PUR), polystyrene (PS), polycaprolactone (PCL), and polyamide 6 (PA6). The antibacterial activity of all nanofiber materials against E. coli was activated by visible light and it was dependent on oxygen permeability/diffusion coefficients and the diameter of the polymeric nanofibers. This activity is based on oxidation ability of singlet oxygen O2(1Δg) that is generated upon irradiation. All tested nanofiber materials exhibited prolonged antibacterial properties, even in the dark after long-duration irradiation. The post-irradiation effect was explained by the photogeneration of H2O2, which provided the material with long-lasting antibacterial properties.
    Trvalý link: http://hdl.handle.net/11104/0201101