Počet záznamů: 1

A single dose of an inhibitor of cyclooxygenase 2, meloxicam, administered shortly after irradiation increases survival of lethally irradiated mice

  1. 1.
    0365878 - BFU-R 2012 RIV US eng J - Článek v odborném periodiku
    Hofer, Michal - Pospíšil, Milan - Dušek, L. - Hoferová, Zuzana - Weiterová, Lenka
    A single dose of an inhibitor of cyclooxygenase 2, meloxicam, administered shortly after irradiation increases survival of lethally irradiated mice.
    Radiation Research. Roč. 176, č. 2 (2011), s. 269-272 ISSN 0033-7587
    Grant CEP: GA ČR(CZ) GA305/08/0158
    Grant ostatní:GA ČR(CZ) GAP303/11/0128
    Program:GA
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: cyclooxygenase-2 inhibition * lethal irradiation * survival
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 2.684, rok: 2011

    We have found that meloxicam, a cyclooxygenase-2 inhibitor, administered in a single dose shortly, i.e. 1 hour, after lethal irradiation, increases survival of irradiated mice. Possible mechanisms of the therapeutic effects of meloxicam administered early after irradiation are discussed.
    Trvalý link: http://hdl.handle.net/11104/0201020