Počet záznamů: 1

Spontaneous in vitro IL-6 production in various intestinal segments in patients with inflammatory bowel diseases

  1. 1.
    0361618 - MBU-M 2012 RIV CZ eng J - Článek v odborném periodiku
    Drastich, P. - Frolová-Břízová, Lenka - Zanvit, P. - Špičák, J. - Tlaskalová-Hogenová, Helena
    Spontaneous in vitro IL-6 production in various intestinal segments in patients with inflammatory bowel diseases.
    Folia Microbiologica. Roč. 56, č. 3 (2011), 185-190 ISSN 0015-5632
    Grant CEP: GA AV ČR 1QS500200572; GA ČR GA305/08/0535; GA ČR GD310/08/H077; GA MŠk 2B06155
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: NECROSIS-FACTOR-ALPHA * ULCERATIVE-COLITIS * CROHNS-DISEASE
    Kód oboru RIV: EC - Imunologie
    Impakt faktor: 0.677, rok: 2011

    Interleukin-6 (IL-6) plays an important role in regulation of intestinal inflammatory processes in inflammatory bowel disease (IBD). The levels of IL-6 in media from cultured biopsy samples were determined by ELISA in 14 Crohn’s disease (CD) patients, 17 patients with ulcerative colitis (UC), and 24 healthy controls in terminal ileum, cecum, and rectum. Results were confirmed by measuring mRNA expression in selected patients. In CD patients, there were increased levels of IL-6 (expressed in picograms per milligram of biopsy tissue mass) in terminal ileum compared with controls
    Trvalý link: http://hdl.handle.net/11104/0198895