Počet záznamů: 1

Neonatal colonization of mice with Lactobacillus plantarum producing the aeroallergen Bet v 1 biases towards Th1 and T-regulatory responses upon systemic sensitization

  1. 1.
    0361615 - MBU-M 2012 RIV DK eng J - Článek v odborném periodiku
    Schwarzer, Martin - Repa, A. - Daniel, C. - Schabussova, I. - Hrnčíř, Tomáš - Pot, B. - Štěpánková, Renata - Hudcovic, Tomáš - Pollak, A. - Tlaskalová, Helena - Wiedermann, U. - Kozáková, Hana
    Neonatal colonization of mice with Lactobacillus plantarum producing the aeroallergen Bet v 1 biases towards Th1 and T-regulatory responses upon systemic sensitization.
    Allergy. Roč. 66, č. 3 (2011), 368-375 ISSN 0105-4538
    Grant CEP: GA AV ČR IAA500200710; GA ČR GA303/09/0449; GA MŠk 2B06155
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: germ-free mice * allergy * mucosal immunity
    Kód oboru RIV: EC - Imunologie
    Impakt faktor: 6.271, rok: 2011

    The use of recombinant lactic acid bacteria (LAB) as vehicles for mucosal delivery of recombinant allergens is an attractive concept for antigen-defined allergy prevention/treatment. Interventions with LAB are of increasing interest early in life when immune programming is initiated. Here, we investigated the effect of neonatal colonization with a recombinant LAB producing the major birch pollen allergen Bet v 1 in a murine model of type I allergy
    Trvalý link: http://hdl.handle.net/11104/0198892