Počet záznamů: 1

Sigma factors and promoters in Corynebacterium glutamicum

  1. 1.
    0360900 - MBU-M 2012 RIV NL eng J - Článek v odborném periodiku
    Pátek, Miroslav - Nešvera, Jan
    Sigma factors and promoters in Corynebacterium glutamicum.
    Journal of Biotechnology. Roč. 154, 2-3 (2011), s. 101-113 ISSN 0168-1656
    Grant CEP: GA ČR GC204/09/J015
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Corynebacterium glutamicum * Sigma factors * Promoters
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 3.045, rok: 2011

    Corynebacterium glutamicum genome codes for 7 sigma subunits (factors) of RNA polymerase (RNAP). Each sigma factor is responsible for recognizing promoters of genes belonging to a regulon (sigmulon) involved in specific functions of the cell. Promoters of individual classes recognized by different sigma factors are compiled and the respective consensus sequences of their key recognition motifs (-35 and -10 regions) are derived. In a number of genes, two or more promoters controlled by the same or different sigma factors were discovered. These multiple, overlapping or dual promoters contribute to a complex gene transcription control mechanisms that integrate internal and external signals and tune gene expression in cells as required by environmental and physiological conditions
    Trvalý link: http://hdl.handle.net/11104/0198343