Počet záznamů: 1

Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats

  1. 1.
    0360808 - MBU-M 2012 RIV GB eng J - Článek v odborném periodiku
    Julien, S. - Julien, T. - Ziemssen, F. - Arango-Gonzalez, B. - Beck, S. - Thielecke, H. - Bueth, H. - van Vlierberghe, S. - Šírová, Milada - Rossmann, Pavel - Říhová, Blanka - Schacht, E. - Dubruel, P. - Zrenner, E. - Schraermeyer, U.
    Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats.
    Biomaterials. Roč. 32, č. 16 (2011), s. 3890-3898 ISSN 0142-9612
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Ophthalmology * Biocompatibility * Cell viability
    Kód oboru RIV: EC - Imunologie
    Impakt faktor: 7.404, rok: 2011

    Subretinal implants aim to replace the photoreceptor function in patients suffering from degenerative retinal disease by topically applying electrical stimuli in the subretinal space. Critical obstacles in the design of high-resolution subretinal implants include the proximity of stimulating electrodes to the target cells and enabling nutrient flow between the retina and the choroid. The present work evaluates the adhesion, migration and survival of retinal cells on an ultrathin (5 mu m), highly porous (circle divide 1 mu m spaced 3 gm), gelatin-coated polyimide (PI) membrane
    Trvalý link: http://hdl.handle.net/11104/0006502