Počet záznamů: 1

Age-dependent remodelling of ionotropic signalling in cortical astroglia

  1. 1.
    0359954 - UEM-P 2012 RIV US eng J - Článek v odborném periodiku
    Lalo, U. - Palygin, O. - North, R. A. - Verkhratsky, Alexei - Pankratov, Y.
    Age-dependent remodelling of ionotropic signalling in cortical astroglia.
    Aging Cell. Roč. 10, č. 3 (2011), s. 392-402 ISSN 1474-9718
    Grant CEP: GA ČR GA305/08/1384
    Výzkumný záměr: CEZ:AV0Z50390703
    Klíčová slova: astrocytes * aging * synaptic transmission
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 6.265, rok: 2011

    Here, we demonstrated marked age-dependent changes in ionotropic receptors (AMPA, P2X and NMDA) in astrocytes and their role in GSCs generation. Our results demonstrate that fast synaptic transmission between neurones and astrocytes in neocortex that may be involved in information processing in neuronal-glial networks undergoes remodelling during brain maturation and aging.
    Trvalý link: http://hdl.handle.net/11104/0197627