Počet záznamů: 1
Age-dependent remodelling of ionotropic signalling in cortical astroglia
- 1.0359954 - ÚEM 2012 RIV US eng J - Článek v odborném periodiku
Lalo, U. - Palygin, O. - North, R. A. - Verkhratsky, Alexei - Pankratov, Y.
Age-dependent remodelling of ionotropic signalling in cortical astroglia.
Aging Cell. Roč. 10, č. 3 (2011), s. 392-402. ISSN 1474-9718. E-ISSN 1474-9726
Grant CEP: GA ČR GA305/08/1384
Výzkumný záměr: CEZ:AV0Z50390703
Klíčová slova: astrocytes * aging * synaptic transmission
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 6.265, rok: 2011
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0359954_01.pdf
Here, we demonstrated marked age-dependent changes in ionotropic receptors (AMPA, P2X and NMDA) in astrocytes and their role in GSCs generation. Our results demonstrate that fast synaptic transmission between neurones and astrocytes in neocortex that may be involved in information processing in neuronal-glial networks undergoes remodelling during brain maturation and aging.
Trvalý link: http://hdl.handle.net/11104/0197627
Počet záznamů: 1