Počet záznamů: 1

Expression and processing of the TMEM70 protein

  1. 1.
    0359610 - FGU-C 2012 RIV NL eng J - Článek v odborném periodiku
    Hejzlarová, Kateřina - Tesařová, M. - Vrbacká-Čížková, A. - Vrbacký, Marek - Hartmannová, H. - Kaplanová, Vilma - Nosková, L. - Kratochvílová, H. - Buzková, J. - Havlíčková, Vendula - Zeman, J. - Kmoch, S. - Houštěk, Josef
    Expression and processing of the TMEM70 protein.
    Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1807, č. 1 (2011), s. 144-149 ISSN 0005-2728
    Grant CEP: GA MZd(CZ) NS9759; GA MŠk(CZ) 1M0520; GA ČR(CZ) GAP303/11/0970
    Grant ostatní:UK(CZ) 259089; UK(CZ) 56209; UK(CZ) 37710
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: mitochondria * ATP synthase * TMEM70 * biogenesis * import
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 4.843, rok: 2011

    Characterization of TMEM70 protein, the novel ancillary factor of mammalian ATP synthase revealed that it is synthesized as a 29 kDa precursor that is processed to mature 21 kDa form upon import to mitochondria. TMEM70 is located in the inner mitochondrial membrane, as a monomer and dimer. Cellular content and expression of TMEM70 is very low and it is absent in patients with ATP synthase deficiency due to TMEM70 c.317-2A>G mutation
    Trvalý link: http://hdl.handle.net/11104/0197366