Počet záznamů: 1

Japanese encephalitis virus: from genome to infectome

  1. 1.
    0359440 - BC-A 2012 RIV NL eng J - Článek v odborném periodiku
    Unni, S. K. - Růžek, Daniel - Chhatbar, C. - Mishra, R. - Johri, M. K. - Singh, S. K.
    Japanese encephalitis virus: from genome to infectome.
    Microbes and Infection. Roč. 13, č. 4 (2011), 312-321 ISSN 1286-4579
    Výzkumný záměr: CEZ:AV0Z60220518
    Klíčová slova: Japanese encephalitis * Neurotropic infection * Neuropathogenesis * Mosquito borne infections * Arboviral infections
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 3.101, rok: 2011

    Japanese encephalitis virus (JEV) is an arbovirus belonging to the family Flaviviridae. It is maintained in a zoonotic cycle involving pigs, ardeid birds and Culex species of mosquitoes. Humans are accidental/dead end hosts of JEV infection because they cannot sustain high viral titers. Factors affecting the clinical manifestations and pathogenesis of JEV infection are not well understood. Though, vaccines are currently available against JEV, it has to be further improved. Here we review the literature on the JEV life cycle, pathogenesis and host immune responses to JEV infection.
    Trvalý link: http://hdl.handle.net/11104/0197230