Počet záznamů: 1

Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission

  1. 1.
    0359223 - BC-A 2012 RIV AU eng J - Článek v odborném periodiku
    Schwarz, Alexandra - Juarez, J. A. - Richards, J. - Rath, B. - Machaca, V. Q. - Castro, Y. E. - Málaga, E. S. - Levy, K. - Gilman, R. H. - Bern, C. - Verastegui, M. - Levy, M. Z.
    Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission.
    International Journal for Parasitology. Roč. 41, č. 6 (2011), s. 591-594 ISSN 0020-7519
    Grant CEP: GA ČR GPP302/11/P798
    Výzkumný záměr: CEZ:AV0Z60220518
    Klíčová slova: Triatoma infestans * Impregnated net * Sentinel guinea pig * Saliva * Antibody response
    Kód oboru RIV: EC - Imunologie
    Impakt faktor: 3.393, rok: 2011

    Insecticide-impregnated nets can kill triatomine bugs, but it remains unclear whether they can protect against Chagas disease transmission. In a field trial in Quequeña, Peru, sentinel guinea pigs placed in intervention enclosures covered by deltamethrin-treated nets showed significantly lower antibody responses to saliva of Triatoma infestans compared with animals placed in pre-existing control enclosures. Our results strongly suggest that insecticide-treated nets prevent triatomine bites and can thereby protect against infection with Trypanosoma cruzi. Anti-salivary immunoassays are powerful new tools to evaluate intervention strategies against Chagas disease.
    Trvalý link: http://hdl.handle.net/11104/0197050