Počet záznamů: 1

Mutant genetic background affects the functional rearrangement and kinetic properties of JMJD2b histone demethylase

  1. 1.
    0357399 - BFU-R 2011 RIV GB eng J - Článek v odborném periodiku
    Bártová, Eva - Stixová, Lenka - Galiová-Šustáčková, Gabriela - Harničarová, Andrea - Legartová, Soňa - Kozubek, Stanislav
    Mutant genetic background affects the functional rearrangement and kinetic properties of JMJD2b histone demethylase.
    Journal of Molecular Biology. Roč. 405, č. 3 (2011), s. 679-695 ISSN 0022-2836
    Grant CEP: GA ČR(CZ) GAP302/10/1022
    Grant ostatní:GA MŠk(CZ) LC06027; GA MŠk(CZ) LC535
    Program:LC; LC
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: histone code * SUV39h * JMJ2b
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 4.001, rok: 2011

    We have studied dynamics of JMJD2b histone demethylases, which functional characteristics are different in mutant and truncated variants. Important changes in nuclear distribution and kinetics of JMJD2b were observed in prostate cancer cells in comparison with other tumor cells and fibroblasts.
    Trvalý link: http://hdl.handle.net/11104/0195685