Počet záznamů: 1

CGG repeats associated with fragile X chromosome form left-handed Z-DNA structure

  1. 1.
    0356600 - BFU-R 2011 RIV US eng J - Článek v odborném periodiku
    Renčiuk, Daniel - Kypr, Jaroslav - Vorlíčková, Michaela
    CGG repeats associated with fragile X chromosome form left-handed Z-DNA structure.
    Biopolymers. Roč. 95, č. 3 (2011), s. 174-181 ISSN 0006-3525
    Grant CEP: GA ČR(CZ) GA202/07/0094; GA AV ČR(CZ) IAA100040701
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: fragile X chromosome syndrome * Z-DNA * trinucleotide repeats
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 2.870, rok: 2011

    In this work we demonstrate that CGG runs adopt a left-handed Z-DNA structure and its formation increased with increasing number of repeats. We show here that methylation of the (CGG) runs markedly stabilized Z-DNA formation.
    Trvalý link: http://hdl.handle.net/11104/0195084