Počet záznamů: 1

Semisynthetic Lupane Triterpenes with Cytotoxic Activity

  1. 1.
    0355519 - UOCHB-X 2011 RIV US eng M - Část monografie knihy
    Šarek, J. - Kvasnica, Miroslav - Vlk, M. - Biedermann, David
    Semisynthetic Lupane Triterpenes with Cytotoxic Activity.
    Pentacyclic Triterpenes as Promising Agents in Cancer. New York: Nova Publishers, 2010, s. 159-189. ISBN 978-1-60876-973-5
    Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z50200510
    Klíčová slova: triterpenes * cytotoxicity * derivatives
    Kód oboru RIV: FR - Farmakologie a lékárnická chemie

    In this chapter, we will describe important natural and semisynthetic lupane triterpenoids with significant cyototoxic effects on cancer cell lines of different histogenetic origin. The main emphasis will be placed on the synthetic derivatives of betulinic acid, the most important cytotoxic agent among lupane triterpenes and betulin, the most readily available natural lupane from natural sources.
    Trvalý link: http://hdl.handle.net/11104/0194269