Počet záznamů: 1

Production of proteolytic enzymes in mast cells, fibroblasts, vascular smooth muscle and endothelial cells cultivated under normoxic or hypoxic conditions

  1. 1.
    0355375 - FGU-C 2011 RIV CZ eng J - Článek v odborném periodiku
    Maxová, H. - Bačáková, Lucie - Lisá, Věra - Novotná, J. - Tomášová, H. - Vízek, M. - Herget, J.
    Production of proteolytic enzymes in mast cells, fibroblasts, vascular smooth muscle and endothelial cells cultivated under normoxic or hypoxic conditions.
    Physiological Research. Roč. 59, č. 5 (2010), s. 711-719 ISSN 0862-8408
    Grant CEP: GA ČR(CZ) GA305/08/0108; GA MŠk(CZ) 1M0510
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: hypoxia * metalloproteinases * tryptase * chymase * immunofluorescence
    Kód oboru RIV: EI - Biotechnologie a bionika
    Impakt faktor: 1.646, rok: 2010

    We tested in vitro production of MMPs and serine proteases in four cell types cultivated for 48 h under normoxic or hypoxic conditions. Among all cell types, mast cells are the most abundant source of proteolytic enzymes under normoxic and hypoxic conditions. Morover, in these cells hypoxia increases the production of both specific serine proteases trypase and chymase, which can act as MMPs activators
    Trvalý link: http://hdl.handle.net/11104/0194159