Počet záznamů: 1

Ergot alkaloids as chiral selectors in capillary electrophoresis and other electromigration methods

  1. 1.
    0354230 - MBU-M 2011 RIV IN eng J - Článek v odborném periodiku
    Sinibaldi, M. - Messina, A. - Stodůlková, Eva - Flieger, Miroslav
    Ergot alkaloids as chiral selectors in capillary electrophoresis and other electromigration methods.
    Global Journal of Analytical Chemistry. Roč. 1, č. 3 (2010), s. 233-243 ISSN 0976-5514
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: capillary electrophoresis * capillary electrochromatography * chiral analysis
    Kód oboru RIV: CB - Analytická chemie, separace

    This review surveys the accomplishments in enantioseparations by capillary electrophoresis and other lectromigration methods obtained using the semisynthetic ergot alkaloid derivative - terguride and its analogues as the chiral selectors. These selectors exhibited a marked discrimination towards carboxylic groups containing compounds under specific experimental conditions (BGE or buffer pH, % of organic modifier in the mobile phase) hat enhanced stereoselective interactions of the selectant with basic functions of the ergoline skeleton. Substituents in N(1) and urea side chain of terguride affected the discriminative process
    Trvalý link: http://hdl.handle.net/11104/0193279