Počet záznamů: 1

A Versatile Synthesis of Functionalized Pentahelicenes

  1. 1.
    0353234 - UOCHB-X 2011 RIV US eng J - Článek v odborném periodiku
    Songis, Olivier - Míšek, Jiří - Schmid, Markus B. - Kollárovič, Adrian - Stará, Irena G. - Šaman, David - Císařová, I. - Starý, Ivo
    A Versatile Synthesis of Functionalized Pentahelicenes.
    Journal of Organic Chemistry. Roč. 75, č. 20 (2010), s. 6889-6899 ISSN 0022-3263
    Grant CEP: GA AV ČR IAA400550916; GA MŠk LC512
    Grant ostatní: EC Integrated Project Pico Inside(XE) FP6-015847
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: functionalized pentahelicene * synthesis * Suzuki-Miyaura coupling
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 4.002, rok: 2010

    A general synthetic methodology for the preparation of functionalized (hetero)helicenes has been developed. It employs the sequence of a double propargyl organometallics (Li, Mg, Ga/In) addition to a tolan-2,2'-dialdehyde-type intermediate, a cobalt-catalyzed [2 + 2 + 2] cycloisomerization of a triyne intermediate, and a double silica gel-assisted acetic acid elimination to receive pentahelicene followed by palladium catalyzed Suzuki-Miyaura coupling.
    Trvalý link: http://hdl.handle.net/11104/0192535