Počet záznamů: 1

Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet

  1. 1.
    0352895 - MBU-M 2011 RIV JP eng J - Článek v odborném periodiku
    Štěpánková, Renata - Tonar, Z. - Bártová, J. - Nedorost, L. - Rossmann, Pavel - Poledne, R. - Schwarzer, Martin - Tlaskalová-Hogenová, Helena
    Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet.
    Journal of Atherosclerosis and Thrombosis. Roč. 17, č. 8 (2010), s. 796-804 ISSN 1340-3478
    Grant CEP: GA MZd NS9775; GA ČR GA303/08/0367; GA ČR GA305/08/0535; GA AV ČR 1QS500200572; GA MŠk 2B06155
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Germ-free mice * Commensal bacteria * Atherogenesis
    Kód oboru RIV: EC - Imunologie
    Impakt faktor: 2.293, rok: 2010

    The aim of our work was to determine the influence of intestinal bacteria on the development of atherosclerotic lesions using apolipoprotein E (ApoE)-deficient knockout mice. The experiments were performed on ApoE deficient mouse strain C57BL/6, bred under germ-free (GF) conditions for two generations or under conventional conditions with defined microflora (CV).
    Trvalý link: http://hdl.handle.net/11104/0192287