Počet záznamů: 1

Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation

  1. 1.
    0350954 - UOCHB-X 2011 RIV GB eng J - Článek v odborném periodiku
    Hiraoka, N. - Ino, Y. - Sekine, S. - Tsuda, H. - Shimada, K. - Kosuge, T. - Závada, Jan - Yoshida, M. - Yamada, K. - Koyama, T. - Kanai, Y.
    Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation.
    British Journal of Cancer. Roč. 103, č. 7 (2010), s. 1057-1065 ISSN 0007-0920
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: pancreatic cancer * hypoxia * prognostics
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 4.831, rok: 2010

    Hypoxia is a major factor of increased invasivity of cancer, resulting in a poor prognosis. In tumor sections, it is manifested by necrotic foci and expression of CAIX protein. We investigated 248 patients with pancreatic ductal carcinoma and correlated necrosis and CAIX with the lenght of survival. SAIX is a biomarker which can easily be evaluated by independent scientists.
    Trvalý link: http://hdl.handle.net/11104/0190811