Surface plasmon resonance biosensor for parallelized detection of protein biomarkers in diluted blood plasma

0350623 - ÚFE 2011 RIV GB eng J - Článek v odborném periodiku
Piliarik, Marek - Bocková, Markéta - Homola, Jiří
Surface plasmon resonance biosensor for parallelized detection of protein biomarkers in diluted blood plasma.
Biosensors and Bioelectronics. Roč. 26, č. 4 (2010), s. 1656-1661. ISSN 0956-5663. E-ISSN 1873-4235
Grant CEP: GA AV ČR KAN200670701
Výzkumný záměr: CEZ:AV0Z20670512
Klíčová slova: Surface plasmon resonance * Protein array * Cancer marker
Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika
Impakt faktor: 5.361, rok: 2010

Surface plasmon resonance (SPR) biosensor for high-throughput screening of protein biomarkers in diluted blood plasma is reported. The biosensor combines a high-resolution SPR imaging sensor and a high-density protein array with low-fouling background. The biosensor was evaluated for detection of protein biomarkers relevant to cancer diagnostics—human chorionic gonadotropin (hCG) and activated leukocyte cell adhesion molecule (ALCAM) both in buffer and in 10% blood plasma.
Trvalý link: http://hdl.handle.net/11104/0190576