Počet záznamů: 1

Real/time monitoring of biomolecular interactions in blood plasma using a surface plasmon resonance biosensor

  1. 1.
    0350305 - URE-Y 2011 RIV DE eng J - Článek v odborném periodiku
    Špringer, Tomáš - Piliarik, Marek - Homola, Jiří
    Real/time monitoring of biomolecular interactions in blood plasma using a surface plasmon resonance biosensor.
    Analytical and Bioanalytical Chemistry. Roč. 398, č. 5 (2010), s. 1955-1961 ISSN 1618-2642
    Grant CEP: GA AV ČR KAN200670701; GA MŠk OC09058
    Výzkumný záměr: CEZ:AV0Z20670512
    Klíčová slova: surface plasmon resonance * molecular interaction analysis * microfluidics * optical biosensor
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 3.841, rok: 2010

    We report a novel biosenor approach which enables real-time monitoring of biomolecular interactions in complex samples. This approach is demonstrated by investigating model interaction between the human chorionic gonadotropin and its antibody in blood plasma using a surface plasmon resonance biosensor and a novel dispersionless microfluidics. The proposed approach also significantly enhance capability of the biosensor to detect biomolecules in complex samples in terms of detection time and sensitivity.
    Trvalý link: http://hdl.handle.net/11104/0190340