Počet záznamů: 1

Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus

  1. 1.
    0349379 - UEM-P 2011 RIV GB eng J - Článek v odborném periodiku
    Ohbuchi, T. - Sato, K. - Suzuki, H. - Okada, Y. - Dayanithi, Govindan - Murphy, D. - Ueta, Y.
    Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus.
    Journal of Physiology. Roč. 588, č. 12 (2010), s. 2147-2162 ISSN 0022-3751
    Výzkumný záměr: CEZ:AV0Z50390703
    Klíčová slova: hypothalamus * ASIC * oxytocin
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 5.139, rok: 2010

    Body fluid balance requires the release of vasopressin (AVP) from the neurohypophysis. Acid-sensing ion channels (ASICs) are neuronal voltage-insensitive cationic channels that are activated by extracellular acidification. We show that acid-induced ASIC current is enhanced by La- in isolated rat SON MNCs that express an AVP-eGFP transgene suggesting that interaction between ASICs and La- in the SON plays an important role in the regulatory mechanism of body fluid homeostasis
    Trvalý link: http://hdl.handle.net/11104/0189635