Počet záznamů: 1

Preparation of (YCl3)-Y-90 radiopharmaceutical precursor for nuclear medicine using technology of centrifugal extractors

  1. 1.
    0349258 - UJF-V 2011 RIV GB eng J - Článek v odborném periodiku
    Šrank, Jiří - Melichar, František - Filyanin, A.T. - Tomeš, Marek - Beran, Miloš
    Preparation of (YCl3)-Y-90 radiopharmaceutical precursor for nuclear medicine using technology of centrifugal extractors.
    Applied Radiation and Isotopes. Roč. 68, č. 12 (2010), s. 2163-2168 ISSN 0969-8043
    Grant CEP: GA MŠk OE08018
    Výzkumný záměr: CEZ:AV0Z10480505
    Klíčová slova: Y-90 radionuclide precursor * Extraction separation * Centrifugal extractors
    Kód oboru RIV: FR - Farmakologie a lékárnická chemie
    Impakt faktor: 0.999, rok: 2010

    Separation of Y-90 from a parent solution of Sr-90-Y-90 in 05 M nitric acid by two-stage liquid-liquid extraction has been investigated using centrifugal extractors. The extraction agent used was 0.25 M di(2-ethylhexyl)phosphoric acid (D2EHPA) in n-dodecane. Back-extraction used 5 M HCl Evaporation of HCl was performed in a rotary vacuum evaporator. Experience gained during the design, construction and running of more than 100 hot separations is presented A short description of analytical methods used and results of the determination of chemical, radionuclidic and radiochemical purities and sterility are given.
    Trvalý link: http://hdl.handle.net/11104/0006085