Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres

0348754 - ÚŽFG 2011 RIV CZ eng J - Článek v odborném periodiku
Nečas, A. - Plánka, L. - Srnec, R. - Crha, M. - Hlučilová, Jana - Klíma, Jiří - Starý, L. - Křen, L. - Amler, Evžen - Vojtová, L. - Jančář, J. - Gál, P.
Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres.
Physiological Research. Roč. 59, č. 4 (2010), s. 605-614. ISSN 0862-8408. E-ISSN 1802-9973
Grant CEP: GA MŠMT 2B06130
Výzkumný záměr: CEZ:AV0Z50450515; CEZ:AV0Z50390512
Klíčová slova: Cartilaginous Tissue * Defects of Articular Surface * Mesenchymal Stem Cells
Kód oboru RIV: CE - Biochemie
Impakt faktor: 1.646, rok: 2010

The aim of this study was to evaluate macroscopically, histologically and immunohistochemically the quality of newly formed tissue in iatrogenic defects of articular cartilage of the femur condyle in miniature pigs treated with the clinically used method of microfractures in comparison with the transplantation of a combination of a composite scaffold with allogeneic mesenchymal stem cells (MSCs) or the composite scaffold alone.
Trvalý link: http://hdl.handle.net/11104/0189191