Počet záznamů: 1

Oxidative damage to biological macromolecules in Prague bus drivers and garagemen: Impact of air pollution and genetic polymorphisms

  1. 1.
    0347615 - UEM-P 2011 RIV IE eng J - Článek v odborném periodiku
    Bagryantseva, Yana - Novotná, Božena - Rössner ml., Pavel - Chvátalová, Irena - Milcová, Alena - Švecová, Vlasta - Lněničková, Zdena - Solanský, I. - Šrám, Radim
    Oxidative damage to biological macromolecules in Prague bus drivers and garagemen: Impact of air pollution and genetic polymorphisms.
    Toxicology Letters. Roč. 199, č. 1 (2010), s. 60-68 ISSN 0378-4274
    Grant CEP: GA MŽP(CZ) SP/1B3/8/08
    Výzkumný záměr: CEZ:AV0Z50390512
    Klíčová slova: air pollution * bud drivers * oxidative stress
    Kód oboru RIV: DN - Vliv životního prostředí na zdraví
    Impakt faktor: 3.581, rok: 2010

    When compared to control subjects, both garagemen and bus drivers are at higher risk of DNA, RNA and protein damage due to higher exposure to benzene and carcinogenic polycyclic aromatic hydrocarbons. Particular genetic polymorphisms, older age, high plasma concentration of LDL cholesterol and low consumption of vitamin C may increase the level of this risk.
    Trvalý link: http://hdl.handle.net/11104/0188361