Počet záznamů: 1

MicroRNA activity is suppressed in mouse oocytes

  1. 1.
    0346835 - UMG-J 2011 RIV GB eng J - Článek v odborném periodiku
    Ma, J. - Flemr, Matyáš - Stein, P. - Berninger, P. - Malík, Radek - Zavolan, M. - Svoboda, Petr - Schultz, R.M.
    MicroRNA activity is suppressed in mouse oocytes.
    Current Biology. Roč. 20, č. 3 (2010), s. 265-270 ISSN 0960-9822
    Grant CEP: GA ČR GAP305/10/2215; GA MŠk ME09039
    Grant ostatní: EMBO SDIG(DE) project 1483
    Výzkumný záměr: CEZ:AV0Z50520514
    Klíčová slova: miRNA * oocyte * pluripotency
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 10.025, rok: 2010

    Research article describing miRNA pathway analysis, which showed that miRNAs are normally produced but their activity is suppressed. This is a surprising and important discovery in the field of pluripotent stem cells because mikroRNAs are required for defining the cellular identity and their absence in the oocyte suggests a ling to the later establishment of pluripotency.
    Trvalý link: http://hdl.handle.net/11104/0187754
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