Počet záznamů: 1

Effects of gamma irradiation on the DNA-protein complex between the estrogen response element and the estrogen receptor

  1. 1.
    0345749 - UJF-V 2011 RIV GB eng J - Článek v odborném periodiku
    Štísová, Viktorie - Goffinont, S. - Maurizot, M. S. - Davídková, Marie
    Effects of gamma irradiation on the DNA-protein complex between the estrogen response element and the estrogen receptor.
    Radiation Physics and Chemistry. Roč. 79, č. 8 (2010), s. 880-889 ISSN 0969-806X
    Grant CEP: GA MŠk 1P05OC085; GA MŠk OC09012
    Výzkumný záměr: CEZ:AV0Z10480505
    Klíčová slova: DNA-protein complex * estrogen response element * estrogen receptor * ionizing radiation
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 1.132, rok: 2010

    The radiosensitivity in vitro of the complex between ER alpha, a subtype of this receptor, and a DNA fragment bearing ERE, as well as the influence of an estrogen (estradiol) or an anti-estrogen (tamoxifen) on this radiosensitivity were studied. We observed that the complex is destabilized upon irradiation with gamma rays in aerated aqueous solution.
    Trvalý link: http://hdl.handle.net/11104/0186949