Počet záznamů: 1

Growth of Vascular Smooth Muscle Cells on Collagen I Exposed to RBL-2H3 Mastocytoma Cells

  1. 1.
    0345062 - FGU-C 2011 RIV CH eng J - Článek v odborném periodiku
    Maxová, H. - Bačáková, Lucie - Eckhardt, Adam - Mikšík, Ivan - Lisá, Věra - Novotná, J. - Herget, J.
    Growth of Vascular Smooth Muscle Cells on Collagen I Exposed to RBL-2H3 Mastocytoma Cells.
    Cellular Physiology and Biochemistry. Roč. 25, č. 6 (2010), s. 615-622 ISSN 1015-8987
    Grant CEP: GA ČR(CZ) GA305/08/0108; GA MŠk(CZ) 1M0510
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: pulmonary hypertension * collagen degradation * smooth muscle cell proliferation
    Kód oboru RIV: EI - Biotechnologie a bionika
    Impakt faktor: 3.585, rok: 2010

    The aim of this “in vitro” study was to verify that mast cells are capable of splitting collagen and then facilitating the growth of vascular smooth muscle cells (VSMC). Increased growth activity of VSMC was probably due to the fragmentation of collagen by proteases released from RBL-2H3 cells. Mast cells exposed to hypoxia are more capable to split collagen and facilitate the gowth of VSMC
    Trvalý link: http://hdl.handle.net/11104/0186424