Počet záznamů: 1

Serotonin and its 5-HT2 receptor agonist DOI hydrochloride inhibit the oxidative burst in total leukocytes but not in isolated neutrophils

  1. 1.
    0343868 - BFU-R 2011 RIV GB eng J - Článek v odborném periodiku
    Prachařová, Lucie - Okénková, Kateřina - Lojek, Antonín - Číž, Milan
    Serotonin and its 5-HT2 receptor agonist DOI hydrochloride inhibit the oxidative burst in total leukocytes but not in isolated neutrophils.
    Life Sciences. Roč. 86, 13-14 (2010), s. 518-523 ISSN 0024-3205
    Grant CEP: GA ČR(CZ) GA524/07/1511
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: chemiluminescence * oxidative burst * serotonin
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 2.451, rok: 2010

    It was observed that 5-HT and its 5-HTR2 agonist DOI hydrochloride were able to inhibit the luminol-enhanced CL response in activated rat and human total leukocytes, but not in isolated human PMNL. The interpretation of these results could suggest the indirect involvement of 5-HTR2 expressed not on the neutrophil surface but on the surface of other leukocytes.
    Trvalý link: http://hdl.handle.net/11104/0186243