Počet záznamů: 1

SUV39h-independent association of HP1beta with fibrillarin-positive nucleolar regions

  1. 1.
    0343809 - BFU-R 2011 RIV DE eng J - Článek v odborném periodiku
    Harničarová, Andrea - Bártová, Eva - Galiová-Šustáčková, Gabriela - Uhlířová, Radka - Matula, P. - Kozubek, Stanislav
    SUV39h-independent association of HP1beta with fibrillarin-positive nucleolar regions.
    Chromosoma. Roč. 119, č. 3 (2010), s. 227-241 ISSN 0009-5915
    Grant CEP: GA MŠk ME 919; GA AV ČR(CZ) 1QS500040508
    Grant ostatní:GA MŠk(CZ) LC06027; GA MŠk(CZ) LC535; GA MŠk(CZ) 2B06052
    Program:LC; LC
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: SUV39h * histone methyltransferases * chromatin structure
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 4.196, rok: 2010

    Deficiency of histone methyltransferase SUV39h, and/or inhibition of histone deacetylases (HDACi) decreased HP1beta and H3K9 trimethylation at chromocenters, but not in fibrillarin-positive regions that co-localized with RNA Pol I. Similarly, SUV39h- and HDACi-dependent nucleolar rearrangement and inhibition of rDNA transcription did not affect the stability of the HP1beta-fibrillarin.
    Trvalý link: http://hdl.handle.net/11104/0186198