Počet záznamů: 1

Electrochemistry of selected radiosenzitizer-etanidazole

  1. 1.
    0343502 - UFCH-W 2011 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
    Gál, Miroslav - Híveš, J. - Sokolová, Romana - Hromadová, Magdaléna - Kocábová, Jana - Kolivoška, Viliam - Pospíšil, Lubomír
    Electrochemistry of selected radiosenzitizer-etanidazole.
    Sborník přednášek. XXX. Moderní elektroanalytické metody. Ústí nad Labem: BEST servis, 2010 - (Navrátil, T.; Barek, J.), s. 55-59. ISBN 978-80-254-6710-7.
    [Modern Electroanalytical Methods /30./. Jetřichovice (CZ), 24.05.2010-28.05.2010]
    Grant CEP: GA ČR GP203/09/P502; GA MŠk LC510; GA MŠk OC 140
    Výzkumný záměr: CEZ:AV0Z40400503
    Klíčová slova: etanidazole * cyclic voltammetry * radiosensitizers * electrochemical impendance spectroscopy
    Kód oboru RIV: CG - Elektrochemie

    The first electron transfer to radiosensitizer etanidazole (ETN) and ETN radical anion formation in buffered aqueous media was studied by means of voltammetric techniques and Electrochemical Impendance Spectroscopy (EIS). The heterogeneous electron transfer rate constant for the first reduction of ETN (radical anion production) k0 for the redox couple and so called E1,7 potential were calculated. The obtained values of k0 and E1,7 potential indicate that ETN compared to some other possible chemical radiosensitizers requires lower energy to accept the first electron during metabolic pathway.
    Trvalý link: http://hdl.handle.net/11104/0185965