Počet záznamů: 1

Preparation of new 18alpha-oleanane alcohols: synthesis, characterization, and cytotoxic activity

  1. 1.
    0343366 - UOCHB-X 2011 RIV AT eng J - Článek v odborném periodiku
    Kvasnica, Miroslav - Rudovská, I. - Hajduch, M. - Šarek, J.
    Preparation of new 18alpha-oleanane alcohols: synthesis, characterization, and cytotoxic activity.
    Monatshefte fur Chemie. Roč. 141, č. 2 (2010), s. 233-244 ISSN 0026-9247
    Grant CEP: GA AV ČR KAN200200651
    Grant ostatní: GA ČR(CZ) GP203/05/P025; GA ČR(CZ) GA305/09/1216
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: reduction * hydride * ketone * configuration * cytotoxicity
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 1.356, rok: 2010

    New oleanane alcohols and their acetates were prepared using classical reductive reagents (LiA1H4, NaBH4, and B2H6-DMS). These products were tested for cytotoxic activity against T-lymphoblastic leukemia (CEM), human erythromyeloblastoid leukemia (K562), and human melanoma (SK-MEL1) cell lines.
    Trvalý link: http://hdl.handle.net/11104/0005912