Počet záznamů: 1

Thyroid hormones and cardiac arrhythmias

  1. 1.
    0343337 - FGU-C 2011 RIV US eng J - Článek v odborném periodiku
    Tribulová, N. - Knezl, V. - Shainberg, A. - Seki, S. - Soukup, Tomáš
    Thyroid hormones and cardiac arrhythmias.
    Vascular Pharmacology. Roč. 52, 3-4 (2010), s. 102-112 ISSN 1537-1891
    Grant CEP: GA ČR(CZ) GA304/08/0256
    Grant ostatní:VEGA(SK) 2/0049/09; APVV(SK) 51-059505; APVV(SK) 51-017905
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: thyroid hormone * arrhythmias * ion channels * connexin-43
    Kód oboru RIV: FA - Kardiovaskulární nemoci vč. kardiochirurgie
    Impakt faktor: 2.174, rok: 2010

    Chronic changes in the amount of circulating thyroid hormone due to thyroid dysfunction or systemic disease result in structural, electrophysiological and Ca2+ handling remodeling, while acute changes may affect basal activity of cardiac cells membrane systems. Consequently, long-term or rapid modulation of sarcolemmal ion channels, Ca2+ cycling proteins and intercellular communicating channels by thyroid hormone may affect heart function as well as susceptibility of the heart to arrhythmias. This aspect including pro- and anti-arrhythmic potential of thyroid hormone is highlighted in this review
    Trvalý link: http://hdl.handle.net/11104/0185841