Signaling by purinergic receptors and channels in the pituitary gland

0343229 - FGÚ 2011 RIV IE eng J - Článek v odborném periodiku
Stojilkovic, S. S. - He, M. L. - Koshimizu, T. - Balík, A. - Zemková, Hana
Signaling by purinergic receptors and channels in the pituitary gland.
Molecular and Cellular Endocrinology. Roč. 314, č. 2 (2010), s. 184-191. ISSN 0303-7207. E-ISSN 1872-8057
Grant CEP: GA ČR(CZ) GA305/07/0681
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: purinergic receptors * ATP * anterior pituitary
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 4.119, rok: 2010

In the pituitary gland, adenosine 5’-triphosphate is released from the endings of magnocellular hypothalamic neurons and by anterior pituitary cells through still not well-characterized pathway(s). This gland also expresses several members of purinergic receptors: P1, P2X and P2Y. P2X receptors stimulate electrical activity and modulate InsP3-dependent calcium release from intracellular stores, whereas P1 receptors terminate electrical activity. Calcium-mobilizing P2Y receptors are predominantly expressed in non-secretory cells of the anterior and posterior pituitary
Trvalý link: http://hdl.handle.net/11104/0185752