Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene

0342649 - ÚOCHB 2011 RIV CZ eng J - Článek v odborném periodiku
Šála, Michal - Hřebabecký, Hubert - Dračínský, Martin - Masojídková, Milena - De Palma, A. M. - Neyts, J. - Holý, Antonín
Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene.
Collection of Czechoslovak Chemical Communications. Roč. 75, č. 1 (2010), s. 1-20. ISSN 0010-0765
Grant CEP: GA MŠMT 1M0508; GA AV ČR 1QS400550501
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: carbocyclic nucleosides * norbornenes * Coxsackie virus
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.853, rok: 2010

This study concerns synthesis of novel racemic conformationally locked nucleosides with bicyclo[2.2.1]heptene ring system substituted with nucleobase and hydroxymethyl group at positions 5 and 6 and their derivatives (saturated a cis-hydroxylated compounds). Biological activity of the newly prepared compounds is described.
Trvalý link: http://hdl.handle.net/11104/0185329