Počet záznamů: 1

Novel analogues of arginine vasopressin containing alpha-2-indanylglycine enantiomers in position 2

  1. 1.
    0342519 - UOCHB-X 2011 RIV GB eng J - Článek v odborném periodiku
    Kwiatkowska, A. - Sleszyňska, M. - Derdowska, I. - Prahl, A. - Sobolewski, D. - Borovičková, Lenka - Slaninová, Jiřina - Lammek, B.
    Novel analogues of arginine vasopressin containing alpha-2-indanylglycine enantiomers in position 2.
    Journal of Peptide Science. Roč. 16, č. 1 (2010), s. 15-20 ISSN 1075-2617
    Grant ostatní: PSCSR(PL) 0230/B/H03/2008/34; PSCSR(PL) 0230/B/H03/2008/35
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: arginine vasopressin (AVP) analogues * antidiuretic hormone * alpha-2-indanylglycine * conformational restriction
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 1.954, rok: 2010

    Described synthesis and biological properties of 10 new vasopressin analogues modified at position 2 with alpha-2-indanylglycine or its D-enantiomer. The new analogues were moderate or potent OT antagonists (pA2 values ranging from 7.19 to 7.98) and practically did not interact with V(1a) and V(2) receptors.
    Trvalý link: http://hdl.handle.net/11104/0185235