Počet záznamů: 1

N-Trimethylsilyloxyenamines as new aldehyde enolate synthons: general, efficient and diastereoselective aldol reaction with ketals and acetals

  1. 1.
    0342453 - UOCHB-X 2011 RIV GB eng J - Článek v odborném periodiku
    Sonawane, Manoj R. - Císařová, I. - Lyapkalo, Ilya
    N-Trimethylsilyloxyenamines as new aldehyde enolate synthons: general, efficient and diastereoselective aldol reaction with ketals and acetals.
    Chemical Communications. Roč. 46, č. 15 (2010), s. 2656-2658 ISSN 1359-7345
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: N-Trimethylsilyloxyenamines * aldol reaction * diastereoselectivity * Trimethylsilyl trifluoromethanesulfonate
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 5.787, rok: 2010

    E-N-Trimethylsilyloxyenamines, easily accessible from aldonitrones, proved to be excellent nucleophiles in TMSOTfinduced diastereoselective aldol reaction, both with ketals and acetals, proceeding via an extended transition state and leading to a new aldol C–C-bond in the aldonitrone products, that can be readily hydrolysed to the corresponding aldehydes.
    Trvalý link: http://hdl.handle.net/11104/0185185