Počet záznamů: 1

Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain

  1. 1.
    0341847 - FGU-C 2011 RIV US eng J - Článek v odborném periodiku
    Drahota, Zdeněk - Vrbacký, Marek - Nůsková, Hana - Kazdová, L. - Zídek, Václav - Landa, Vladimír - Pravenec, Michal - Houštěk, Josef
    Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain.
    Biochemical and Biophysical Research Communications. Roč. 391, č. 3 (2010), s. 1348-1351 ISSN 0006-291X
    Grant CEP: GA MŠk OC08017; GA MZd(CZ) NR9387; GA MŠk(CZ) 1M0520; GA ČR(CZ) GA301/08/0166
    Grant ostatní: EC(XE) LSHG-CT-2005-019015; Fondation Leducq(FR) 06 CVD 03
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: CD36 * mitochondria * SSO
    Kód oboru RIV: CE - Biochemie
    Impakt faktor: 2.595, rok: 2010

    We investigated effect of SSO on mitochondrial respiration. Experiments in rat liver, heart and kidney mitochondria demonstrated a direct effect on mitochondrial respiratory chain with the most pronounced inhibition of the complex III. The results show that SSO is a potent and irreversible inhibitor of mitochondrial respiratory chain
    Trvalý link: http://hdl.handle.net/11104/0184708