Počet záznamů: 1

CXC and CC chemokines induced in human renal epithelial cells by inflammatory cytokines

  1. 1.
    0341403 - MBU-M 2010 RIV US eng J - Článek v odborném periodiku
    Thornburn, E. - Kolesar, L. - Brabcová, E. - Petříčková, Kateřina - Petříček, Miroslav - Jarešová, M. - Slavcev, A. - Stříž, I.
    CXC and CC chemokines induced in human renal epithelial cells by inflammatory cytokines.
    Acta Pathologica Microbiologica et Immunologica Scandinavica. Roč. 117, č. 7 (2009), s. 477-487 ISSN 0903-4641
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Epithelial cells * chemokines * transplantation
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 1.745, rok: 2009

    Human renal epithelial cells might play an important role during the allograft rejection by producing chemokines in response to proinflammatory cytokines such as tumor necrosis factor (TNF)-alpha and interleukin (IL)-1 beta produced by endothelial and epithelial cells early after transplantation. The production of chemokines allows inflammatory cells to be drawn into the kidney graft and therefore plays a critical role in the pathophysiologic processes that lead to the rejection of renal transplant. In this process, two chemokine superfamilies, the CC and the CXC chemokines, are the most important
    Trvalý link: http://hdl.handle.net/11104/0184404