Počet záznamů: 1

Cell-Mediated Immunity in Cervical Cancer Evolution

  1. 1.
    0341159 - URE-Y 2010 RIV US eng J - Článek v odborném periodiku
    Jandová, Anna - Pokorný, Jiří - Kobilková, J. - Janoušek, M. - Mašata, J. - Trojan, S. - Nedbalová, M. - Dohnalová, A. - Beková, A. - Slavík, V. - Čoček, A. - Sanitrák, J.
    Cell-Mediated Immunity in Cervical Cancer Evolution.
    Electromagnetic Biology and Medicine. Roč. 28, č. 1 (2009), s. 1-14 ISSN 1536-8378
    Grant CEP: GA MŠk OC 288.001
    Výzkumný záměr: CEZ:AV0Z20670512
    Klíčová slova: Biophysics * Cancer * Electromagnetic fields
    Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika
    Impakt faktor: 0.729, rok: 2009

    Cell-mediated immunity (CMI) response to different antigens was examined in healthy women, in patients with cervical precancerous lesions, and in patients with cervical cancer. Cervical lesions were diagnosed by cytological (PAP) smears, from examination by colposcopy, and from punch biopsy material by histology. CMI response is related to specific processes in healthy and cancer cells. CMI was investigated by leukocyte adherence inhibition (LAI) assay using specific antigen (prepared from cervical carcinoma tissue) and non specific antigen (prepared from blood of mice infected by LDHlactate dehydrogenasevirus). The CMI responses of healthy women and cancer patients to the antigens used are different: the majority of T lymphocytes display adherence and non adherence, respectively (but the CMI responses elicited by the antigens are not equal and small quantitative differences are observed).
    Trvalý link: http://hdl.handle.net/11104/0184234