Počet záznamů: 1

Functionalizable surface platform with reduced nonspecific protein adsorption from bull blood plasma - Material selection and protein immobilization optimization

  1. 1.
    0341080 - URE-Y 2010 RIV GB eng J - Článek v odborném periodiku
    Vaisocherová, Hana - Zhang, Z. - Yang, W. - Cao, Z. - Cheng, G. - Taylor, A. D. - Piliarik, Marek - Homola, Jiří - Jiang, S.
    Functionalizable surface platform with reduced nonspecific protein adsorption from bull blood plasma - Material selection and protein immobilization optimization.
    Biosensors and Bioelectronics. Roč. 24, č. 7 (2009), s. 1924-1930 ISSN 0956-5663
    Grant CEP: GA AV ČR KAN200670701
    Výzkumný záměr: CEZ:AV0Z20670512
    Klíčová slova: Zwitterionic poly(carboxybetaine) * Functionalization * Ultra-low fouling
    Kód oboru RIV: CD - Makromolekulární chemie
    Impakt faktor: 5.429, rok: 2009

    Zwitterionic polymers are investigated as ultra-low fouling and functionalizable coatings for biosensorsand microarrays to enable detections in real-world complex media. The effect of the spacer length between the two charged groups on the nonfouling properties of zwitterionic poly(carboxybetaine acrylamide) (polyCBAA) was studied in blood plasma and serum. A polyCBAA-coated surface was functionalized with antibodies using a simple and fast amino coupling chemistry for direct protein immobilization.
    Trvalý link: http://hdl.handle.net/11104/0184178