Počet záznamů: 1

Alkaloid Cluster Gene ccsA of the Ergot Fungus Claviceps purpurea Encodes Chanoclavine I Synthase, a Flavin Adenine Dinucleotide-Containing Oxidoreductase Mediating the Transformation of N-Methyl-Dimethylallyltryptophan to Chanoclavine I

  1. 1.
    0340888 - MBU-M 2011 RIV US eng J - Článek v odborném periodiku
    Lorenz, N. - Olšovská, Jana - Šulc, Miroslav - Tudzynski, P.
    Alkaloid Cluster Gene ccsA of the Ergot Fungus Claviceps purpurea Encodes Chanoclavine I Synthase, a Flavin Adenine Dinucleotide-Containing Oxidoreductase Mediating the Transformation of N-Methyl-Dimethylallyltryptophan to Chanoclavine I.
    Applied and Environmental Microbiology. Roč. 76, č. 5 (2010), s. 1822-1830 ISSN 0099-2240
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: BERBERINE BRIDGE ENZYME * BIOSYNTHESIS * IDENTIFICATION
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 3.778, rok: 2010

    rgot alkaloids are indole-derived secondary metabolites synthesized by the phytopathogenic ascomycete Claviceps purpurea. In wild-type strains, they are exclusively produced in the sclerotium, a hibernation structure; for biotechnological applications, submerse production strains have been generated by mutagenesis. It was shown previously that the enzymes specific for alkaloid biosynthesis are encoded by a gene cluster of 68.5 kb. This ergot alkaloid cluster consists of 14 genes coregulated and expressed under alkaloid-producing conditions
    Trvalý link: http://hdl.handle.net/11104/0184036