Počet záznamů: 1

Automated Ambient Desorption-Ionization Platform for Surface Imaging Integrated with a Commercial Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

  1. 1.
    0340257 - MBU-M 2010 RIV US eng J - Článek v odborném periodiku
    Pól, Jaroslav - Vidová, Veronika - Kruppa, G. - Kobliha, Václav - Novák, Petr - Lemr, Karel - Kotiaho, T. - Kostiainen, R. - Havlíček, Vladimír - Volný, Michael
    Automated Ambient Desorption-Ionization Platform for Surface Imaging Integrated with a Commercial Fourier Transform Ion Cyclotron Resonance Mass Spectrometer.
    Analytical Chemistry. Roč. 81, č. 20 (2009), s. 8479-8487 ISSN 0003-2700
    Grant CEP: GA MŠk LC07017
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: ATMOSPHERIC-PRESSURE PHOTOIONIZATION * COMPREHENSIVE CLASSIFICATION-SYSTEM * mass spectrometry
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 5.214, rok: 2009

    A fully automated atmospheric pressure ionization platform has been built and coupled with a commercial high-resolution Fourier transform ion cyclotron resonance mass spectrometer (FTICR-MS) instrument. The outstanding performance of this instrument allowed screening on the basis of exact masses in imaging mode. The main novel aspect was in the integration of the atmospheric pressure ionization imaging into the current software for matrix-assisted laser desorption ionization (MALDI) imaging, which allows the user of this commercial dual-source mass spectrometer to perform MALDI-MS and different ambient MS imaging from the same user interface and to utilize the same software tools. Desorption electrospray ionization (DESI) and desorption atmospheric pressure photoionization (DAPPI) were chosen to test the ambient surface imaging capabilities of this new ionization platform
    Trvalý link: http://hdl.handle.net/11104/0183538