Počet záznamů: 1

Cross sections of the reaction Pa-231(d,3n)U-230 for the production of U-230/Th-226 for targeted alpha therapy

  1. 1.
    0338852 - UJF-V 2010 RIV US eng J - Článek v odborném periodiku
    Morgenstern, A. - Lebeda, Ondřej - Štursa, Jan - Capote, R. - Sin, M. - Bruchertseifer, F. - Zielinska, B. - Apostolidis, C.
    Cross sections of the reaction Pa-231(d,3n)U-230 for the production of U-230/Th-226 for targeted alpha therapy.
    Physical Review. C. Roč. 80, č. 5 (2009), 054612/1-054612/6 ISSN 0556-2813
    Výzkumný záměr: CEZ:AV0Z10480505
    Klíčová slova: Pa-231 * U-230 * Th-226 * reaction cross section * targeted alpha therapy
    Kód oboru RIV: BG - Jaderná, atomová a mol. fyzika, urychlovače
    Impakt faktor: 3.477, rok: 2009

    U-230 and its daughter nuclide Th-226 are novel therapeutic nuclides for application in targeted alpha therapy of cancer. We investigated the feasibility of producing U-230/Th-226 via deuteron irradiation of Pa-231 according to the reaction Pa-231(d,3n)U-230. The experimental excitation function for a deuteron-induced reaction on Pa-231 is reported for the first time. Cross sections were measured using thin targets of Pa-231 prepared by electrodeposition and U-230 yields were analysed using alpha spectrometry. Beam energies were calculated from measured beam orbits and compared with the values obtained via monitor reactions on aluminium foils using high-resolution gamma spectrometry and IAEA recommended cross sections. Beam intensities were determined using a beam current integrator. The experimental cross sections are in excellent agreement with model calculations allowing for deuteron breakup using the EMPIRE 3 code.
    Trvalý link: http://hdl.handle.net/11104/0182514