Počet záznamů: 1

TMEM70 protein — A novel ancillary factor of mammalian ATP synthese

  1. 1.
    0338634 - FGU-C 2010 RIV NL eng J - Článek v odborném periodiku
    Houštěk, Josef - Kmoch, S. - Zeman, J.
    TMEM70 protein — A novel ancillary factor of mammalian ATP synthese.
    Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1787, č. 5 (2009), s. 529-532 ISSN 0005-2728
    Grant CEP: GA MŠk(CZ) 1M0520; GA MZd(CZ) NS9759
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: ATP synthase * disease * TMEM70
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 3.688, rok: 2009

    Mutations in TMEM70 gene encoding a 30kD mitochondrial protein of unknown function prevent ATP synthase biogenesis and are found in most known patients with mitochondrial disease due to decreased ATP synthase content. TMEM70 represents a new ancillary factor of mammalian ATP synthase. As revealed by phylogenetic analysis, TMEM70 is specific for higher eukaryotes
    Trvalý link: http://hdl.handle.net/11104/0182358