Počet záznamů: 1

Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells

  1. 1.
    0333896 - UMG-J 2010 RIV GR eng J - Článek v odborném periodiku
    Kovář, J. - Ehrlichová, M. - Šmejkalová, Barbora - Zanardi, I. - Ojima, I. - Gut, I.
    Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells.
    Anticancer Research. Roč. 29, č. 8 (2009), s. 2951-2960 ISSN 0250-7005
    Grant CEP: GA ČR(CZ) GD204/05/H023
    Grant ostatní: GA MZd(CZ) NR9426; GA ČR(CZ) GA301/09/0362
    Výzkumný záměr: CEZ:AV0Z50520514
    Klíčová slova: Cell death * taxane SB-T-1216 * paclitaxel
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 1.428, rok: 2009

    Cell death induced by both paclitaxel and novel taxane SB-T-1216 in breast cancer cells is associated with caspase activation and with the formation of interphase microtubule bundles. Novel taxane SB-T-1216, but not paclitaxel, seems to be capable of inducing cell death without the accumulation of cells in the G(2)/M phase.
    Trvalý link: http://hdl.handle.net/11104/0178771