Počet záznamů: 1

Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via Stille coupling and biological activity of the target substances

  1. 1.
    0332654 - UOCHB-X 2010 RIV CZ eng J - Článek v odborném periodiku
    Balšánek, V. - Tichotová, L. - Kuneš, J. - Špulák, M. - Pour, M. - Votruba, Ivan - Buchta, V.
    Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via Stille coupling and biological activity of the target substances.
    Collection of Czechoslovak Chemical Communications. Roč. 74, 7/8 (2009), s. 1161-1178 ISSN 0010-0765
    Grant CEP: GA MŠk 1M0508
    Grant ostatní:GA ČR(CZ) GA203/07/1302
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: Pd catalysis * Cross-coupling reactions * heterocycles * tetrazoles
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 0.856, rok: 2009

    A series of tetrazoles linked to the butenolide core via benzene rings were prepared by the Stille coupling reaction of alpha-(tributylstannyl)butenolides and 5-(alkylsulfanyl)-1-(4-iodophenyl)tetrazoles, and the compounds were tested for antifungal and cytostatic activity.
    Trvalý link: http://hdl.handle.net/11104/0177849