Počet záznamů: 1

The Fischer 344 rat as a model of presbycusis

  1. 1.
    0332199 - UEM-P 2011 RIV NL eng J - Článek v odborném periodiku
    Syka, Josef
    The Fischer 344 rat as a model of presbycusis.
    Hearing Research. Roč. 264, 1-2 (2010), s. 70-78 ISSN 0378-5955
    Grant CEP: GA ČR GA309/07/1336; GA MŠk(CZ) LC554
    Výzkumný záměr: CEZ:AV0Z50390703
    Klíčová slova: Rat * Fischer 344 * Presbycusis
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 2.428, rok: 2010

    Pronounced hearing loss at the end of the second year, the rapid deterioration of distortion product otoacoustic emissions with the majority of outer hair cells being present and morphologically intact, produced apparently by the disruption of prestin, and deterioration of acoustical signal processing within central auditory system supports the idea that the Fischer 344 rat strain may serve as a suitable model for studying the mechanisms of presbycusis, its prevention and treatment.
    Trvalý link: http://hdl.handle.net/11104/0177523