Počet záznamů: 1

Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana

  1. 1.
    0331523 - UBO-W 2010 RIV US eng J - Článek v odborném periodiku
    Pfefferle, S. - Oppong, S. - Drexler, J. F. - Gloza-Rausch, F. - Ipsen, A. - Seebens, A. - Müller, M. A. - Annan, A. - Vallo, Peter - Adu-Sarkodie, Y. - Kruppa, T. F. - Drosten, C.
    Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana.
    Emerging Infectious Diseases. Roč. 15, č. 9 (2009), s. 1377-1384 ISSN 1080-6040
    Grant ostatní: German Ministry of Education and Research(XE) SSPE-CT-2005-022639; FP7(XE) INFRASTRUCTURES-2008-No 228292; Bundesamt für Bevölkerungsschutz und Katastrophenhilfe(DE) BBK-F-440-00-1
    Výzkumný záměr: CEZ:AV0Z60930519
    Klíčová slova: SARS-like * phylogenetic analysis * RNA * gastroenteritis * prevalence * diversity
    Kód oboru RIV: FN - Epidemiologie, infek. nemoci a klin. imunologie
    Impakt faktor: 6.794, rok: 2009

    We tested 12 bat species in Ghana for coronavirus (CoV) RNA. The virus prevalence in insectivorous bats (n=123) was 9.76%. CoV was not detected in 212 fecal samples from Eidolon helvum fruit bats. Leaf-nosed bats pertaining to Hipposideros ruber by morphology had group 1 and group 2 CoVs. Virus concentrations were <45,000 copies/100 mg of bat feces. The diversified group 1 CoV shared a common ancestor with the human common cold virus hCoV-229E but not with hCoV-NL63, disputing hypotheses of common human descent. The most recent common ancestor of hCoV-229E and GhanaBt-CoVGrp1 existed in ≈1686–1800 AD. The GhanaBt-CoVGrp2 shared an old ancestor (≈2,400 years) with the severe acute respiratory syndrome–like group of CoV.
    Trvalý link: http://hdl.handle.net/11104/0177018